GHK-Cu — Copper Peptides in Skin, Hair, and Regeneration Research

Published by Proliven Labs — For Research Use Only

GHK-Cu (glycyl-L-histidyl-L-lysine: copper(II)) is a naturally occurring copper-binding peptide found in human plasma and tissue. It has been studied for decades due to its potential regenerative properties in skin, hair follicles, and connective tissue. Researchers have investigated its role in wound healing, anti-aging, and tissue remodeling.

GHK-Cu appears to act as a signaling molecule that supports cell repair and modulates gene expression. Research shows it may:

• Promote collagen and elastin production
• Stimulate skin and hair follicle stem cells
• Reduce inflammation and oxidative stress
• Influence gene expression related to repair, remodeling, and aging reversal

GHK-Cu has been studied across multiple areas of interest:

• Skin regeneration: GHK-Cu may improve skin elasticity, reduce wrinkles, and accelerate wound healing in animal models.
• Hair growth: Research indicates activation of hair follicle cells and prolongation of the growth phase (anagen).
• Anti-aging & gene repair: Studies show GHK-Cu can influence over 4,000 genes, including those involved in inflammation suppression and tissue repair.
• Antioxidant activity: The peptide may scavenge free radicals and enhance cellular defense mechanisms.

• 📄 GHK-Cu and gene expression in aging skin — PubMed
• 📄 Copper peptide effects on hair follicle activation — PubMed
• 📄 Skin wound healing and collagen regeneration — PubMed

GHK-Cu is not approved for human or cosmetic use. It is supplied strictly for laboratory research purposes. Proliven Labs manufactures GHK-Cu in small batches, third-party tests each lot, and provides Certificates of Analysis (COAs) to qualified researchers.

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