Jun 6, 2025

What Is a COA? Understanding Third-Party Peptide Testing

Published by Proliven Labs — For Research Use Only

Why Peptide Purity and Identity Matter

In peptide research, the integrity of your compound determines the reliability of your results. That's why serious researchers rely on Certificates of Analysis (COAs) — independent laboratory reports that confirm the identity and purity of a given peptide batch.

At Proliven Labs, every peptide we manufacture is third-party tested by ISO-accredited analytical labs. This ensures that our customers receive compounds that meet or exceed 99% purity, with validated identity through methods like mass spectrometry and HPLC.

What Is a Certificate of Analysis (COA)?

A COA is a lab-generated document that includes:

  • Peptide name and batch number
  • Purity percentage (e.g., 99.5%)
  • Testing methods used (e.g., HPLC, MS, NMR)
  • Identity confirmation via molecular weight or sequence analysis
  • Storage & stability recommendations

Why We Use Independent Labs

Many manufacturers perform in-house testing — but this creates a conflict of interest. At Proliven Labs, we believe trust starts with transparency. Our COAs are issued by third-party labs that have no financial ties to us. These labs are equipped with advanced instrumentation and follow rigorous validation protocols.

Our COAs are batch-specific, meaning you can verify exactly what’s in your vial — no guesswork, no marketing fluff.

Sample COA Parameters

  • Purity: 99.5% by HPLC
  • Molecular Weight: Confirmed by mass spectrometry
  • Appearance: White lyophilized powder
  • Storage: -20°C recommended
  • Form: Acetate salt, sterile-filtered

How to Verify a COA

Every vial from Proliven Labs includes a lot number. You can use this number to request or access the COA specific to your product. We are also working on a COA Lookup feature to make this process faster for researchers.

Research Use Only

All peptides offered by Proliven Labs are strictly for laboratory research use. Our commitment to third-party testing is designed to support responsible science — not unverified or off-label use.

Disclaimer: This article is intended for educational purposes only. Proliven Labs does not promote the use of peptides in humans or animals outside approved research contexts. Always refer to COAs for the most accurate batch-specific data.

Written by Danny Shaftel

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