Epithalon 10 mg Vial

Epithalon (also known as Epitalon or Epithalamin) is a premium, high-purity synthetic tetrapeptide meticulously designed to replicate the structure and function of the naturally occurring polypeptide epithalamin, produced by the pineal gland. Comprising a precise sequence of four amino acids (Alanine-Glutamic Acid-Aspartic Acid-Glycine), Epithalon has a molecular formula of C14H22N4O9 and a molecular weight of 390.349 g/mol. Supplied as a lyophilized white powder in 10 mg vials, this research-grade peptide is optimized for in vitro laboratory studies, offering researchers a powerful tool to explore telomere biology, cellular aging, and related mechanisms.

• Exceptional Purity: ≥99% purity, rigorously verified through third-party HPLC and mass spectrometry testing, ensuring unparalleled quality for precise and reproducible research results.
• Telomerase Activation: Extensively studied for its ability to stimulate telomerase activity, a key enzyme responsible for elongating telomeres, thereby supporting chromosomal stability and delaying cellular senescence.
• Anti-Aging Research Potential: Epithalon has garnered significant attention in gerontological research for its ability to extend lifespan and mitigate age-related changes. Studies on fruit flies, rats, and human cell lines have demonstrated prolonged cell viability, with some models showing up to a 52% reduction in mortality rates in healthy subjects and 27% in disease-prone models.
• Melatonin Regulation: Research indicates Epithalon enhances melatonin production, contributing to improved circadian rhythm regulation and sleep quality in experimental models, a critical factor in aging and metabolic studies.
• Antioxidant and Cellular Protection: Exhibits robust antioxidant properties, reducing oxidative stress by neutralizing free radicals and supporting cellular health, making it a valuable asset in studies of oxidative damage and tissue repair.
• Broad Research Applications: Ideal for investigations into telomere maintenance, epigenetic regulation, immune function, oncology, and age-related disease prevention, offering versatile applications in cutting-edge biomedical research.

• Unit Size: 10 mg per vial
• CAS Number: 307297-39-8
• PubChem CID: 219042
• Appearance: White lyophilized powder
• Solubility: Reconstitute with sterile bacteriostatic water (not included) for research use
• Storage Conditions: Store at -20°C in a dry, dark environment to maintain stability; reconstituted peptide should be stored at 2-8°C and used within 20-30 days to ensure potency
• Stability: Lyophilized form remains stable for up to 24 months when stored properly

Epithalon is a cornerstone peptide in longevity and cellular biology research. Its ability to activate telomerase and extend telomeres has profound implications for understanding cellular aging. In vitro studies have shown Epithalon enables human fibroblast cell lines to surpass the Hayflick limit—the point at which cells cease division due to telomere shortening—potentially through epigenetic reactivation of telomerase genes. Animal studies, particularly in rodents, have demonstrated significant lifespan extension, with some protocols reducing age-related mortality by up to 50%. Additional research highlights Epithalon’s role in:

• Oncology: Inhibiting tumor growth in certain models, potentially through enhanced immune function and DNA repair mechanisms.
• Immune System Support: Strengthening immune responses in aging models, improving resistance to infections and stressors.
• Neuroendocrine Regulation: Normalizing pineal gland function and melatonin synthesis, critical for circadian and hormonal balance.
• Oxidative Stress Reduction: Protecting cells from free radical damage, a key factor in aging and degenerative diseases.

• Intended Use: Exclusively for in vitro research and laboratory experimentation by qualified professionals. Not approved for human or veterinary use.
• Reconstitution: Dissolve in 1-2 mL of sterile bacteriostatic water using sterile vials and insulin syringes (not included). Gently swirl to mix; avoid vigorous shaking to preserve peptide integrity.
• Research Protocols: Commonly studied protocols include:
  • Russian Protocol: 10 mg daily for 10 days, administered twice annually.
  • Ukrainian Protocol: 5 mg daily for 10 days, repeated biannually.
  • Low-Dose Protocol: 1-2 mg daily for 10-20 days, depending on study design.
• Administration in Research: Typically administered via subcutaneous or intramuscular injection in animal models or applied to cell cultures for in vitro studies.
• Safety Note: Bodily introduction into humans or animals is strictly prohibited by law. Researchers must adhere to institutional and regulatory guidelines.

• Use in controlled laboratory settings with appropriate personal protective equipment (PPE).
• Potential side effects in research settings may include minor injection site reactions (e.g., redness or swelling). Consult peer-reviewed literature for comprehensive safety data.
• Avoid contamination by using sterile techniques during reconstitution and handling.
• Dispose of unused or expired peptide in accordance with local biohazard regulations.

Studies indicate that CJC-1295 and Ipamorelin are generally well-tolerated, with mild side effects including:

• Injection site reactions (redness, itching, or pain)
• Headaches, nausea, or lightheadedness
• Water retention or flushing (rare with recommended doses)
• Low-purity peptides may increase side effect risks, so sourcing from reputable vendors with lab-tested products is critical. Long-term effects remain understudied, necessitating cautious research protocols.

Epithalon 10 mg is sold strictly for research purposes and is not intended for human consumption, medical, or veterinary applications. This product has not been evaluated or approved by the FDA or any other regulatory body. Researchers are solely responsible for ensuring compliance with all applicable laws, ethical guidelines, and safety protocols. Sourcing from reputable vendors is critical to avoid counterfeit or contaminated products.